Comparative Evaluation of Antioxidant Activity in Extracts and Fractions from Leaves and Stem of Geophila obvallata (Schumach.) Didr
Comparative Evaluation of Antioxidant Activity in Extracts and Fractions from Leaves and Stem of Geophila obvallata (Schumach.) Didr: Background: Oxidative stress, a condition characterized by an imbalance between reactive oxygen species (ROS) and antioxidant defences, is increasingly implicated in various human diseases. Medicinal plants with potent antioxidant properties hold promise for therapeutic interventions against oxidative stress-related pathologies. This study aimed to comparatively evaluate the antioxidant potential of leaf and stem extracts and fractions derived from Geophila obvallata. Methods: Methanolic extracts of G. obvallata leaves and stems were subjected to solvent partitioning to obtain fractions based on polarity. Total phenolic content (TPC) and total flavonoid content (TFC) were determined. The antioxidant capacities of the extracts and fractions were assessed using established assays, including hydroxyl radical scavenging (HRSA) and ABTS+ cation radical scaven...